Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors from the central nervous procedure, conolidine modulates alternate molecular targets. A Science Advancements examine observed that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability... https://jeffreycjnoo.blogdigy.com/the-basic-principles-of-alternative-natural-pain-relief-to-replace-traditional-painkillers-60491512